More than 110 drugs, capable of penetrating this elusive barrier are currently being evaluated for the treatment of CNS disorders; there are nearly 35 technology platforms for the development of BBB penetrant drugs, claims Roots Analysis

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The concept of BBB penetration is anticipated to bring about a paradigm shift in modern healthcare. In fact, experts believe that there is an important relationship between the recent pandemic of Coronavirus disease (COVID-19) and cerebrovascular system, presenting commercial opportunities for players engaged in the development of BBB penetrating drugs.


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The USD 940 million (by 2030) financial opportunity within the BBB market has been analyzed across the following segments:

  • Type of Payment Model Adopted
  • Upfront payments
  • Milestone payments


  • Type of Molecule
  • Small Molecules
  • Biologics


  • Target Disease Indication
  • Brain Metastases in Breast Cancer
  • Glioblastoma Multiforme
  • Hunter Syndrome
  • Hurler Syndrome


  • Leading Technology Platforms
  • G®-Technology
  • J-Brain Cargo® Technology
  • LRP-1 Technology
  • Trojan Horse Technology


  • Leading Drug Developers
  • 2-BBB
  • Angiochem
  • ArmaGen
  • JCR Pharmaceuticals


  • Key Geographical Regions
  • North America
  • Europe
  • Asia-Pacific



The Blood-Brain Barrier (BBB) Market (2nd Edition), 2020-2030: Focus on Non-Invasive Drug Delivery Technology Platforms and Therapeutics report features the following companies, which we identified to be key players in this domain:

  • Angiochem
  • ArmaGen
  • BioArctic
  • Cyclenium Pharma
  • Denali Therapeutics
  • ICB International
  • Iproteos
  • JCR Pharmaceuticals
  • Lauren Sciences
  • Medesis Pharma
  • Ossianix
  • Vect-Horus


Table of Contents


  1. Preface

    2. Executive Summary

  2. Introduction
  3. Market Landscape: Non-Invasive BBB Penetration
  4. Market Landscape: BBB Penetrating Drugs
  5. Company Profiles
  6. Technology Competitiveness Analysis
  7. Non-Invasive BBB Penetration Technologies: Popular Approaches
  8. Partnerships and Collaborations
  9. Analysis of Recent Licensing Agreements
  10. Funding and Investment Analysis
  11. Patent Analysis
  12. Drug Development Strategy Analysis
  13. Market Potential of Key Neurological Disorders


  1. Likely Partner Analysis


  1. Market Forecast


  1. Conclusion


  1. Executive Insights


  1. Appendix 1: Tabulated Data


  1. Appendix 2: List of Companies and Organizations


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About Roots Analysis

Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at [email protected]


Contact Information

Roots Analysis Private Limited

Gaurav Chaudhary

+1 (415) 800 3415

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